1. Studying the role of persister cells in chronic infections.
2. Mechanisms of persister formation and maintenance in Pseudomonas aeruginosa.
Publications:
Mulcahy LR, Nillni EA. (2007) Discovery of new peptides from old prohormones: insights for energy balance and beyond. Biosci 12:3545-53 [PDF]
Mulcahy LR, Barker AJ, Nillni EA. (2006) Disruption of disulfide bond formation alters the trafficking of prothyrotropin releasing hormone (proTRH)-derived peptides. Regul Pept. 133(1-3):123-33 [Link]
Mulcahy LR, Vaslet CA, Nillni EA. (2005) Prohormone-convertase 1 processing enhances post-Golgi sorting of prothyrotropin-releasing hormone-derived peptides. J Biol Chem. 280(48):39818-26 [PDF]
Nillni EA, Xie W, Mulcahy L, Sanchez VC, Wetsel WC. (2002) Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice. J Biol Chem. 277(50):48587-95 [PDF]